A valid assay for the pharmacokinetic study of gallic acid from choerospondiatis fructus in rabbit plasma by LC/MS/MS
发布时间：2025-04-30
点击次数：
- 发布时间：
- 2025-04-30
- 论文名称：
- A valid assay for the pharmacokinetic study of gallic acid from choerospondiatis fructus in rabbit plasma by LC/MS/MS
- 发表刊物：
- J. Liq. Chromatogr. Related Technol
- 摘要：
- The calibration curve was linear in the range of 0.5-400 ng · mL-1 for plasma samples. The limit of detection was 200 pg · mL-1. Intra-and inter-day coefficients of variation were less than 8.0% and intra- and inter-day accuracies were within ±5.0% of the known concentrations. Finally, this assay was used to study the pharmacokinetics of GA in rabbit plasma following ingestion of Choerospondiatis fructus extracts. The statistical results indicated that the plasma drug concentration time course in rabbit was a 2-compartment open model.
- 合写作者：
- Zhao XF, Zhang WJ et al
- 卷号：
- 30
- 页面范围：
- 235-244
- 是否译文：
- 否
- 发表时间：
- 2007-04-05