A New USP Class VI-compliant substrate for manufacturing disposable microfluidic devices
- Release Time:2025-04-30
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Date:
2025-04-30Title of Paper:
A New USP Class VI-compliant substrate for manufacturing disposable microfluidic devicesJournal:
Lab on A ChipSummary:
As microfluidic systems transition from research tools to disposable clinical-diagnostic devices, new
substrate materials are needed to meet both the regulatory requirement as well as the economics of
disposable devices. This paper introduces a UV-curable polyurethane-methacrylate (PUMA) substrate
that has been qualified for medical use and meets all of the challenges of manufacturing microfluidic
devices. PUMA is optically transparent, biocompatible, and exhibits high electroosmotic mobility
without surface modification. We report two production processes that are compatible with the existing
methods of rapid prototyping and present characterizations of the resultant PUMA microfluidic
devices.Co-author:
Jason S. Kuo , Laiying Ng , ... , yongxi zhaoTranslation or Not:
NoDate of Publication:
2009-02-10
