Dynamical mechanisms for sensitive response of aperiodic firing cells to external stimulation
发布时间：2025-04-30
点击次数：
- 发布时间：
- 2025-04-30
- 论文名称：
- Dynamical mechanisms for sensitive response of aperiodic firing cells to external stimulation
- 发表刊物：
- CHAOS SOLITONS & FRACTALS
- 摘要：
- An interesting phenomenon that aperiodic firing neurons have a higher sensitivity to drugs than periodic firing
neurons have been reported for the chronically compressed dorsal root ganglion neurons in rats. In this study, thedynamical mechanisms for such a phenomenon are uncovered from the viewpoint of dynamical systems theory. We use the Rose–Hindmarsh neuron model to illustrate our opinions. Periodic orbit theory is introduced to characterize the dynamical behavior of aperiodic firing neurons. It is considered that bifurcations, crises and sensitive dependence of chaotic motions on control parameters can be the underlying mechanisms. And then, a similar analysis is applied to the modified Chay model describing the firing behavior of pancreatic beta cells. The same dynamical mechanisms can be obtained underlying that aperiodic firing cells are more sensitive to external stimulation than periodic firing ones. As a result, we conjecture that sensitive response of aperiodic firing cells to external stimulation is a universal property of
excitable cells.
- 合写作者：
- Yong Xie , Jian-Xue Xu , San-Jue Hu , Yan-Mei Kang
- 卷号：
- 22 (1)
- 页面范围：
- 151-160
- 是否译文：
- 否
- 发表时间：
- 2003-12-29