孙丽娜 博士

副教授

博士生导师

病原生物学与免疫学系

西安交通大学基础医学院

中国西部科技创新港转化医学研究院

陕西省免疫健康重点实验室

主持国家自然科学基金面上项目和青年项目、陕西省重点实验室项目，参与国家自然科学基金重大项目等。共发表科研论文30余篇，主要代表作发表在Signal Transduction and Targeted Therapy、Cellular & Molecular Immunology、Nature Communications、Journal of Clinical Investigation、Cell Death & Disease、The Journal of Immunology等杂志。获得美国和中国发明专利各1项。担任基金评审、论文评审、答辩委员和学术杂志客座编辑等。参与《医学免疫学（第 4 版）数字教材》、《词说免疫学》、《生物医学前沿》等著作编著。荣获西部联盟第一届课程思政案例大赛特等奖。担任本科生、研究生和留学生的《医学免疫学》和《免疫学实验》等课程。指导本科生参加陕西省“大学生创新训练项目”和西安交通大学第三十六届“腾飞杯”创新创业大赛。

2021年9月 － 至今：          副教授、博导，西安交通大学

2020年3月 － 2021年9月：Principle investigator，信达生物制药（苏州）有限公司

2018年3月 － 2020年3月：Research Associate，美国佐治亚大学

2014年5月 － 2018年3月：博士后，美国佐治亚大学

2007年9月 － 2014年1月：博士，中国科学院动物研究所

1. Sun, Lina; Zhang, Cangang; Jiao, Anjun; Su, Yanhong; Zhang, Tianzhe; Wang, Qianhao; Ge, Yao; Chen, Yang; Yuan, Ning; Zhang, Lianjun;  Sun, Chenming; Chen, Liang; Ye, Lilin; Zhang, Baojun* ; CCR2⁺ monocytes promote memory CD8⁺ T cell differentiation via membrane-bound TGF-β, Cellular & Molecular Immunology，2025, 22(8): 869-888

2. Sun, Lina; Zhang, Tianzhe; Ge, Yao; Zhang, Baojun* ; FTO controls CD8⁺ T cell survival and effector response by modulating m6A methylation of Fas, Cell Death & Disease, 2025,16(1)

3. Sun, Lina; Jiao, Anjun; Liu, Haiyan; Ding, Renyi; Yuan, Ning; Yang, Biao; Zhang, Cangang;Jia, Xiaoxuan; Wang, Gang; Su, Yanhong; Zhang, Dan; Shi, Lin; Sun, Chenming*; Zhang, Aijun*;Zhang, Lianjun*;Zhang, Baojun* ; Targeting a disintegrin and metalloprotease (ADAM) 17-CD122 axis enhances CD8⁺ T cell effector differentiation and anti-tumor immunity, Signal Transduction and Targeted Therapy, 2024, 9(1): 0-152

4. Zhang, Cangang; Ren, Tao; Zhao, Xiaofan; Su, Yanhong; Wang, Qianhao; Zhang, Tianzhe; He,Boxiao; Chen, Yabing; Wu, Ling-Yun; Sun, Lina*; Zhang, Baojun*; Xia, Zheng* ; Biologically informed machine learning modeling of immune cells to reveal physiological and pathological aging process, Immunity and Ageing, 2024, 21(1): 0-74

5. Liu, Haiyan; Feng, Zhao; Jiao, Anjun; Lan, Linbo; Ding, Renyi; Li, Wenhua; Zheng, Huiqiang; Su, Yanhong; Jia, Xiaoxuan; Zhang, Dan; Yang, Xiaofeng*; Zhang, Lianjun; Sun, Lina*; Zhang, Baojun* ; The Transcription Factor Zfp335 Promotes Differentiation and Survival of Effector Th1 Cells by Directly Regulating Lmna Expression, The Journal of Immunology, 2024, 212(11): 1714-1721

6. Yuan, Ning; Su, Yanhong; Gao, Yang; Yang, Biao; Zhang, Tianzhe; Wang, Qianhao; Zhang,Dan; Shi, Lin; Jiao, Anjun*; Lei, Lei*; Sun, Lina*; Zhang, Baojun* ; Med1 controls thymic T-cell migration into lymph node through enhancer-based Foxo1-Klf2 transcription program, European Journal of Immunology, 2024, 54(10)

7. Sun, Lina; Su, Yanhong; Jiao, Anjun; Wang, Xin; Zhang, Baojun* ; T cells in health and disease, Signal Transduction and Targeted Therapy, 2023, 8(1): 0-235

8. Wang, Xin; Sun, Lina*; Yang, Biao; Li, Wenhua; Zhang, Cangang; Yang, Xiaofeng; Sun, Yae;Shen, Xiaonan; Gao, Yang; Ju, Bomiao; Gao, Yafeng; Liu, Dan; Song, Jiapeng; Jia, Xiaoxuan; Su,Yanhong; Jiao, Anjun; Liu, Haiyan; Zhang, Lianjun; He, Lan; Lei, Lei*; Chen, WanJun*; Zhang, Baojun* ; Zfp335 establishes eTreg lineage and neonatal immune tolerance by targeting Hadha-mediated fatty acid oxidation, Journal of Clinical Investigation, 2023, 133(20): 0-e166628

9. Jiao, Anjun; Liu, Haiyan; Ding, Renyi; Zheng, Huiqiang; Zhang, Cangang; Feng, Zhao; Lei, Lei; Wang, Xin; Su, Yanhong; Yang, Xiaofeng; Sun, Chenming; Zhang, Lianjun; Bai, Liang*; Sun, Lina*; Zhang, Baojun* ; Med1 Controls Effector CD8⁺ T Cell Differentiation and Survival through C/EBP β-Mediated Transcriptional Control of T-bet, The Journal of Immunology, 2022, 209(5): 855-863

10. Sun, Lina; Amy V., Paschall; Dustin R., Middleton; Mayumi, Ishihara; Ahmet, Ozdilek;Paeton L., Wantuch; Javid, Aceil; Jeremy A., Duke; Celia C., LaBranche; Michael, Tiemeyer; Fikri Y., Avci; Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help, Nature Communications, 2020, 11(1): 0-2550