何旺骁

教授，博士生导师

国家青年长江学者

陕西省千人计划学者

西安交通大学第一附属医院

hewangxiao5366@xjtu.edu.cn

靶向蛋白-蛋白相互作用的多肽药物开发与成药研究

致病蛋白靶向功能调控和蛋白功能研究

专业关键词：

多肽药物，多肽化学，蛋白质化学，纳米医学，纳米药剂学

Liu W*, Liu Y, Zhang L, Li L, Yang W, Li J, He W*. Nucleic acid spheres for treating capillarisation of liver sinusoidal endothelial cells in liver fibrosis. Nature Communications. 2025, 16(1): 4517.

He W*, Ding F, Zhang L, Liu W*. In situ osteogenic activation of mesenchymal stem cells by the blood clot biomimetic mechanical microenvironment. Nature Communications. 2025, 16(1): 1162.

Liu D, Yan J*, Ma F, Wang J, Yan S, He W*. Reinvigoration of cytotoxic T lymphocytes in microsatellite instability-high colon adenocarcinoma through lysosomal degradation of PD-L1. Nature Communications. 2024, 15(1): 6922.

Liu N, Zheng X, Yan J, Jiang A, Yao Y, He W*. Reversing MET-Mediated Resistance in Oncogene-Driven NSCLC by MET-Activated Wnt Condensative Prodrug. Advanced Science. 2024, 11(30): e2400603.

Yang W, Liu W*, Li X, Yan J*, He W*. Turning chiral peptides into a racemic supraparticle to induce the self-degradation of MDM2. Journal of Advanced Research. 2023,45:59-71.（ESI高被引 TOP1%）