1. 国家自然科学基金委员会，青年科学基金项目，2024-01-01 至 2026-12-31，30 万元，主持。

 
2. 陕西省三秦英才引进计划，青年项目，2024-12-31 至 2030-12-30，30 万元，主持。 

3. 西安交通大学，青年拔尖人才支持计划（B 类），2024-12-31 至 2030-12-30，100 万元，主持。 

4. 国家自然科学基金委员会，国际（地区）合作与交流项目，2020-01-01 至 2023-12-31，100 万元，项目骨干。

 
5. 中国科学技术部, 政府间国际科技创新合作重点专项, 2019-08-01 至 2022-07-31，488 万元，项目骨干。 

41. Zhang Xun*, Wang Jun*, Gao Heqi*. Recent Advances in the Design of Biomedical Materials for Cancer Theranostics. Curr. Med. Chem., 2025, 32, 211-213.

40. Zhang Jingtian†, Jiao Di†, Qi Xinwen, Zhang Yufan, Liu Xiaoang, Pan Tengwu, Gao Heqi, Liu Zhao yun*, Ding Dan*, Feng Guangxue*. An Albumin-Photosensitizer Supramolecular Assembly with Type I ROS-Induced Multifaceted Tumor Cell Deaths for Photodynamic Immunotherapy. Adv. Sci. 2025, 12, 2410405.

39. Li Cong†, Yue Xin†, Gao Heqi, Meng Qingxun, Qu Jiafei, Chen Yao, Ding Dan*, Xin Jingrui*, Shen Jing*. Injectable composite hydrogels based on minocycline and NIR photothermal therapy for antimicrobial and bone regeneration. Biomater. Adv. 2025, 177, 214397.

38. Gao Heqi, Zhang Tingting, Lei Yunxiang*, Jiao Di, Yu Bo, Yuan Wang Zhang, Ji Jian, Jin Qiao*, Ding Dan*. An Organophosphorescence Probe with Ultralong Lifetime and Intrinsic Tissue Selectivity for Specific Tumor Imaging and Guided Tumor Surgery. Angew. Chem. Int. Ed. 2024, 63, e202406651 (VIP article).

37. Gao Heqi†, Yao Yiming†, Li Cong, Zhang Jingtian, Yu Haoyun, Yang Xiaodi, Shen Jing, Liu Qian, Xu Ruitong, Gao Xike*, Ding Dan*. Fused Azulenyl Squaraine Derivatives Improve Phototheranostics in the Second Near-Infrared Window by Concentrating Excited State Energy on Non-Radiative Decay Pathways. Angew. Chem. Int. Ed. 2024, 63, e202400372 (VIP article).

36. Chen Haitao†, Bao Pingping†, Lv Yonghui, Luo Rui, Deng Jiayin*, Yan Yingbin*, Ding Dan*, Gao Heqi*. Enhancing NIR-II Imaging and Photothermal Therapy for Improved Oral Cancer Theranostics by Combining TICT and Aggregation-Induced Emission. ACS Appl. Mater. Inter., 2023, 49, 56895-56908.

35. Fang Yuan, Liu Xin, Guo Hanqiong, Zhang Yujie, Wu Haotian, Zhou Xiao, Chen Xiying, Qin Haijuan, Gao Heqi*, Liu, Yaqing*. AIE Bioconjugates for Accurate Identification and In Vivo Targeted Treatment of Bacterial Infection Based on Bioorthogonal Reaction. Adv. Healthcare Mater. 2023, 2300044.

34. Gao Heqi†, Qi Xinwen†, Zhang Jingtian†, Wang Nan, Xin Jingrui, Jiao Di, Liu Kaining, Qi Ji, Guan Yong*, Ding Dan*. Smart One-for-All Agent with Adaptive Functions for Improving Photoacoustic /Fluorescence Imaging-Guided Photodynamic Immunotherapy. Small methods, 2023, e2201582.

33. Gao Xiangyu†; Gao Heqi†; Yue Kangyi†; Cao Xiuli; Yang Erwan; Zhang Zhuoyuan; Huang Yutao; Li Xin; Ding Dan; Luo Peng*; Jiang Xiaofan*. Observing Extracellular Vesicles Originating from Endothelial Cells in Vivo Demonstrates Improved Astrocyte Function Following Ischemic Stroke via Aggregation-Induced Emission Luminogens. ACS Nano, 2023, 17, 16174-16191.

32. Zhang Xinhui†; Gao Heqi†; Wei Daohe; Pei Xiaoying; Zhang Yue; Wang Jian; Ding Dan*; Chang Jin*; Wu Xiaoli*. ROS Responsive Nanoparticles Encapsulated with Natural Medicine Remodel Autophagy Homeostasisin Breast Cancer. ACS Appl. Mater. Interfaces 2023, 15, 29827–29840.

31. Ji Shenglu†*, Li Songge†, Gao Heqi†, Wang Jiayang, Wang Kaiyuan, Nan Wenbin, Chen Hongli, Hao Yongwei*. An AIEgen-based "turn-on" probe for sensing cancer cells and tiny tumors with high furin expression. Biomater. Sci. 2023, 11, 2221-2229.

30. Zhang Xiaoyan, Wang Kefei, Gao Zhiyuan, Wu Zelin, Liu Wei, Li Jisen, Gao Heqi, Wei Jun, Ding Dan, Zheng Wenting, An Aggregation-Induced Emission Molecule-Assembled Nanovaccine with Self-Adjuvanted Function for Cancer Immunotherapy. Adv. Funct. Mater. 2023, 2302118.

29. Gao Heqi†, Zhang Jingtian†, Qi Xinwen, Jiao Di, Hong Yuning, Shan Ke, Kong Xianglong, Ding Dan. Polymerization-Amplified Photoacoustic Signal by Enhancing Near-Infrared Light-Harvesting Capacity and Thermal-to-Acoustic Conversion. Chin. J. Polym. Sci. 2022, 40, 1090–1100.

28. Chen chao†, Gao Heqi†, Ou Hanlin†, Kwork Ryan T.K., Tang Youhong, Zheng Donghui, Ding dan*. Amplification of Activated Near-Infrared Afterglow Luminescence by Introducing Twisted Molecular Geometry for Understanding Neutrophil-Involved Diseases. J. Am. Chem. Soc. 2022, 144, 3429−3441 (Cover paper, ESI highly cited paper).

27. Wang Kai†, Gao Heqi†, Zhang Yuwen, Yan Hongyu, Si Jianghua, Mi Xingyan, Xia Shuang, Feng Xuequan, Liu Dingbin, Kong Deling, Wang Ting*, Ding Dan*. Highly Bright AIE Nanoparticles by Regulating the Substituent of Rhodanine for Precise Early Detection of Atherosclerosis and Drug Screening. Adv. Mater. 2022, 34, 2106994.

26. Xiao Fuming†, Gao Heqi†, Lei Yunxiang*, Dai Wenbo, Liu Miaochang, Zheng Xiaoyan, Cai Zhengxu, Huang Xiaobo*, Wu Huayue, Ding Dan*. Guest-host doped strategy for constructing ultralong-lifetime near-infrared organic phosphorescence materials for bioimaging. Nat. Commun. 2022, 13, 186 (ESI highly cited paper).

25. Cao Hongmei†, Gao Heqi†, Wang Lanxing, Cheng Yuanqiu, Wu Xiaoli, Shen Xiaohong, Wang Hang, Wang Zhen, Zhan Panpan, Liu Jianfeng, Li Zongjin, Kong Deling, Shi Yang, Ding Dan, Wang Yuebing*. Biosynthetic Dendritic Cell-Exocytosed Aggregation-Induced Emission Nanoparticles for Synergistic Photodynamic Immunotherapy. ACS Nano, 2022, 16, 13992-14006.

24. Wang Zhenjie, Wang Yuehua, Gao Heqi, Tang Chenhong, Feng Zhenzhen, Lin Ling, Che Siyao*, Luo Chunmei, Ding Dan, Zheng Donghui*, Yu Zhiqiang*, Peng Zhenwei. Phototheranostic nanoparticles with aggregation-induced emission as a four-modal imaging platform for image-guided photothermal therapy and ferroptosis of tumor cells. Biomaterials, 2022, 289, 121779.

23. Zhang Guoqiang, Gao Zhiyuan, Zhang Jingtian, Ou Hanlin, Gao Heqi, Kwork Ryan T.K., Ding Dan*, Tang Ben Zhong*. A wearable AIEgen-based lateral flow test strip for rapid detection of SARS-CoV-2 RBD protein and N protein. Cell Rep. Phys. Sci. 2022, 3, 100740.

22. Gao Heqi†, Duan Xingchen†, Jiao Di, Zeng Yi, Zheng Xiaoyan*, Zhang Jingtian, Ou Hanlin, Qi Ji*, Ding Dan*. Boosting Photoacoustic Effect via Intramolecular Motions Amplifying Thermal-to-Acoustic Conversion Efficiency for Adaptive Image-Guided Cancer Surgery. Angew. Chem. Int. Ed. 2021, 60, 21047 (Hot paper).

21. Gao Heqi, Gao Zhiyuan, Jiao Di, Zhang Jingtian, Li Xiaolin, Tang Qiyun*, Shi Yang*, Ding Dan*. Boosting Room Temperature Phosphorescence Performance by Alkyl Modification for Intravital Orthotopic Lung Tumor Imaging. Small, 2021, 17, 2005449 (Cover paper).

20. Gao Heqi†; Zhang Lanrui†; Lian Xiaoli; Wang Yue; Jiang Shihui; Wang Guanhua; Dai Xiaohua; Zou Huiru*; Ding Dan. A dentin hypersensitivity treatment using highly stable photothermal conversion nanoparticles. Mater. Chem. Front., 2021, 5, 3388-3395 (Cover paper).

19. Gao Heqi, Jiao Di, Ou Hanlin, Zhang Jingtian, Ding Dan*. High Performing Aggregation-Induced Emission Nanoprobes for Image-Guided Cancer Surgery. Acta Chim Sinica, 2021, 79, 319-325 (Cover paper).

18. Wang Yunsheng†, Gao Heqi†, Yang Jie*, Fang Manman, Ding Dan*, Tang Ben Zhong*, Li Zhen*. High performance of simple organic phosphorescence host-guest materials and their application in time-resolved bio-imaging. Adv. Mater., 2021, 33, 2007811 (ESI highly cited paper).

17. Zeng Sheng†, Gao Heqi†, Li Chuang, Xing Shaoqiang, Xu Zhaoliang, Liu Qian*, Feng Guangxue*, Ding Dan*. Boosting Photothermal Theranostics via TICT and Molecular Motions for Photohyperthermia Therapy of Muscle-Invasive Bladder Cancer. Adv. Healthcare Mater. 2021, 10, 2101063.

16. Jiang Zhen, Sun Boyang, Wang Yueqi, Gao Heqi, Ren He, Zhang Hao, Lu Tong, Ren Xiangkui, Wei Wei, Wang Xiaoli, Zhang Lei, Li Jiao, Ding Dan, Lovell Jonathan F., Zhang Yumiao*. Surfactant-Stripped Micelles with Aggregation-Induced Enhanced Emission for Bimodal Gut Imaging In Vivo and Microbiota Tagging Ex Vivo. Adv. Healthcare Mater. 2021, 10, 2100356.

15. Chen Xiaohui†; Gao Heqi†; Deng Yongyan; Jin, Qiao; Ji Jian; Ding Dan. Supramolecular Aggregation-Induced Emission Nanodots with Programmed Tumor Microenvironment Responsiveness for Image-Guided Orthotopic Pancreatic Cancer Therapy. ACS Nano, 2020, 14, 5121-5134.

14. Li Jun†; Gao Heqi†; Liu Ruihua; Chen Chao; Zeng Sheng; Liu Qian; Ding Dan. Endoplasmic reticulum targeted AIE bioprobe as a highly efficient inducer of immunogenic cell death. Sci. China Chem. 2020, 63, 1428-1434.

13. Gao Zhengfeng†; Gao Heqi†; Zheng Debin; Xu Tengyan; Chen, Yaoxia; Liang, Chunhui; Wang Ling; Ding Dan; Yang Zhimou. beta-galactosidase responsive AIE fluorogene for identification and removal of senescent cancer cells. Sci. China Chem. 2020, 63, 398-403.

12. Huang Qiuqin, Gao Heqi, Yang Shuming, Ding Dan, Lin Zhenghuan, Ling Qidan. Ultrastable and colorful afterglow from organic luminophores in amorphous nanocomposites: advanced anti-counterfeiting and in vivo imaging application. Nano Res. 2020, 12, 1035-1043.

11. Cao Hongmei; Cheng Yuanqiu; Gao Heqi; Zhuang Jie; Zhang Weiguang; Bian Qiang; Wang Fang; Du Yuan; Li Zongjin; Kong Deling; Ding Dan; Wang Yuebing. In Vivo Tracking of Mesenchymal Stem Cell-Derived Extracellular Vesicles Improving Mitochondria! Function in Renal Ischemia- Reperfusion Injury. ACS Nano 2020, 14, 4014-4026.

10. Gao Fangli; Wu Jin; Gao Heqi; Hu Xueyan; Liu Lihua; Midgley Adam C.; Liu, Qiqi; Sun Zhiyuan; Liu Yijin; Ding, Dan; Wang Yanming; Kong Deling; Huang Xinglu. Hypoxia-tropic nanozymes as oxygen generators for tumor-favoring theranostics. Biomaterials 2020, 230, 119635.

9. Zhao Xiujie; Fan Zhiwen; Qiao Yanqi; Chen Yun; Wang, Shuo; Yue Xinmin; Shen Tangliang; Liu Wenting; Yang Jie; Gao Heqi; Zhan Xuelin; Shang Luqing; Yin, Yongmei; Zhao, Wei; Ding, Dan; Xi Rimo; Meng Meng. AIEgens Conjugation Improves the Photothermal Efficacy and Near-Infrared Imaging of Heptamethine Cyanine IR-780. ACS Appl. Mater. Inter. 2020, 12, 16114-16124.

8. Gao Heqi†; Bao Pingping†; Dai Shuxin; Liu Ruihua; Ji Shenglu; Zeng Sheng; Shen Jing; Liu Qian; Ding Dan. Far-Red/Near-Infrared Emissive (1,3-Dimethyl) barbituric Acid-Based AIEgens for High-Contrast Detection of Metastatic Tumors in the Lung. Chem-Asian J, 2019, 14, 871-876.

7. He Zihan†; Gao Heqi†; Zhang Shitong; Zheng Shuyuan; Wang, Yunzhong; Zhao Zihao; Ding Dan; Yang Bing; Zhang Yongming; Yuan Wang Zhang. Achieving Persistent, Efficient, and Robust Room-Temperature Phosphorescence from Pure Organics for Versatile Applications. Adv. Mater. 2019, 31, 1807222.

6. Zhang Tingting†; Gao Heqi†; Lv Anqi; Wang Ziyi; Gong Yongyang; Ding Dan; Ma Huili; Zhang Yongming; Yuan Wang Zhang. Hydrogen bonding boosted the persistent room temperature phosphorescence of pure organic compounds for multiple applications. J. Mater. Chem. C. 2019, 7, 9095-9101.

5. Yang Jie†; Gao Heqi†; Wang Yunsheng; Yu Yun; Gong Yanbin; Fang Manman; Ding Dan; Hu Wenping; Tang Ben Zhong; Li Zhen. The odd-even effect of alkyl chain in organic room temperature phosphorescence luminogens and the corresponding in vivo imaging. Mater. Chem. Front. 2019, 3, 1391-1397.

4. Cao Hongmei; Yue Zhiwei; Gao Heqi; Chen Chao; Cui, Kaige; Zhang Kaiyue; Cheng Yuanqiu; Shao Guoqiang; Kong Deling; Li Zongjin; Ding Dan; Wang Yuebing. In Vivo Real-Time Imaging of Extracellular Vesicles in Liver Regeneration via Aggregation-Induced Emission Luminogens. ACS Nano, 2019, 13, 3522-3533.

3. Ou Hanlin; Li Jun; Chen Chao; Gao Heqi; Xue Xue; Ding Dan. Organic/polymer photothermal nanoagents for photoacoustic imaging and photothermal therapy in vivo. Sci. China Mater. 2019, 62, 1740-1758.

2. Gao Heqi; Zhang Xiaoyan; Chen Chao; Li Kai; Ding Dan. Unity Makes Strength: How Aggregation-Induced Emission Luminogens Advance the Biomedical Field. Adv. Biosys. 2018, 2, 1800074.

1. Ji Shenglu; Gao Heqi; Mu Wancen; Ni Xiang; Yi Xiaoyong; Shen Jing; Liu Qian; Bao Pingping; Ding Dan. Enzyme-instructed self-assembly leads to the activation of optical properties for selective fluorescence detection and photodynamic ablation of cancer cells. J Mater. Chem. B 2018, 6, 2566-2573.

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