发布时间：2025-04-30

论文名称：Hybrid biointerface engineering nanoplatform for dual-targeted tumor hypoxia relief and enhanced photodynamic therapy

发表刊物：JOURNAL OF COLLOID AND INTERFACE SCIENCE

摘要：The clinical application of photodynamic therapy (PDT) is limited by the lack of tumor selectivity of photo-sensitizer (PS) and the hypoxic tumor microenvironment (TME). To address these limitations of PDT, we developed a hybrid engineered biointerface nanoplatform that integrated anti-epidermal growth factor receptor (EGFR)-aptamer (EApt)-modified liposomes with tumor cell membranes (TMs) to create M/L-EApt. M/L-EApt exhibited enhanced stability and significant dual-targeting ability, enabling selectively accumulate in hypoxic

合写作者：Xueyan Zhen, Lanlan Jia, Qingyu Tang, Ying Zhao, Peishan Li, Jing Li, Xiaoyu Xie*, Sicen Wang*

卷号：647

页面范围：211-223

是否译文：否

发表时间：2023-07-02