发布时间：2025-04-30

论文名称：One-Pot Synthesis of Fluorescent and Cross-Linked Polyphosphazene Nanoparticles for Highly Sensitive and Selective Detection of Dopamine in Body Fluids

发表刊物：RSC Advances

摘要：Highly cross-linked and monodisperse polyphosphazene (PZS) nanoparticles exhibiting strong fluorescence were prepared by the facile one-pot polycondensation of hexachlorocyclotriphosphazene and 4′,5′-dibromofluorescein (DBF). Fluorescent DBF units were ‘immobilized’ and ‘isolated’ in the cross-linked structures to effectively overcome their concentration-quenching effect and improve their photobleaching properties. The resulting DBF–PZS nanoparticles emitted bright yellow fluorescence at any concentration and exhibited excellent resistance to photobleaching as well as interference from bio-molecules such as proteins, ascorbic acid and uric acid. Intriguingly, the fluorescence of the DBF–PZS   nanoparticles was linearly quenched by DA range from 0.5 to 15 μg·mL−1 DA concentration via photoinduced charge transfer. Therefore, DBF–PZS nanoparticles represent a simple but effective, highly sensitive and selective detection method with a direct read out for DA in biological fluids.

合写作者：Wang Daquan; Hu Ying; Meng Lingjie*; Wang Xiaochi; Lu Qinghua *

卷号：5(112)

页面范围：92762-92768

是否译文：否

发表时间：2015-10-19