Papers
Release Time: 2025-04-30Hits:
  • Date:2025-04-30
  • Title of Paper:Prediction of in-vivo joint mechanics of an artificial knee implant using rigid multi-body dynamics with elastic contacts
  • Journal:Proc Inst Mech Eng H
  • Summary:Musculoskeletal (MSK) lower limb models play an important role in predicting joint forces and muscle activation simultaneously and are valuable for investigating clinical issues. However, current computational MSK models of total knee replacement (TKR) rarely consider the bearing surface geometry of the implant. Therefore these models lack detailed information about the contact mechanics and joint motion which are important factors for evaluating clinical performances. This study extended a rigid multi-body dynamics simulation of a lower extremity MSK model to incorporate an artificial knee joint, based upon a novel force-dependent kinematics (FDK) method, to characterize the in vivo joint mechanics during gait cycles. The developed MSK TKR model integrated the rigid skeleton multi-body dynamics and the flexible contact mechanics of the tibio-femoral (TF) and patello-femoral (PF) joints. The predicted contact forces and muscle activation were compared to those in vivo measurements obtained from a single patient with overall good agreements for the medial contact force (RMSE=215 N, ρ=0.96) and lateral contact force (RMSE=179 N, ρ=0.75). Moreover, the developed model also predicted the motion of the TF joint in all degrees of freedom. This new model provides an important step towards the development of a realistic dynamic MSK TKR model to predict in vivo knee joint motion and loading simultaneously. This could offer better opportunity to establish a robust virtual modeling platform for future pre-clinical assessment of knee prosthesis designs, surgical procedures and post-operation rehabilitation.
  • Co-author:Chen ZX, Zhang X, Ardestani M,Wang L, et al.
  • Translation or Not:No
  • Date of Publication:2014-04-01

王玲