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连芩
教授
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Design and fabrication of a novel porous implant with pre-set channels based on ceramic stereolithography for vascular implantation
Release Time:2025-04-30 Hits:
Date:
2025-04-30
Title of Paper:
Design and fabrication of a novel porous implant with pre-set channels based on ceramic stereolithography for vascular implantation
Journal:
Biofabrication
Summary:
Being a multi-etiological factors disease, osteonecrosis of the femoral head affects many
young people, leading to the collapse of the femur head; eventually the hip arthroplasty is
needed if not treated in time. Unfortunately, as yet, no satisfactory therapy to repair necrotic
bone at an early stage is present. Novel implants with pre-set channels were designed for the
treatment of early femoral head necrosis. Ceramic stereolithography was applied to fabricate
the green part from β-TCP powder. Other processes, such as dehydration, rinsing, drying and
sintering, were processed successively. The final ceramic part remains the same as the
engineered part in both shape and internal structure. No significant deformation or crack
occurred. X-ray diffraction showed that no facies changed or chemical reaction occurred
during the fabrication process. The chemical composition remains the same as that of the
original β-TCP powder. The compressive strength is 23.54 MPa, close to that of natural
cancellous bone. Novel implants with a pre-set channel were designed and fabricated for
blood vessel implantation . Bioceramic stereolithography technology based directly on the
CAD model in this research shows advantages in accurate design, optimization of 3D scaffold
and critical control of the fabrication process. This proposed implant shows promising clinical
application in the restoration of early femoral head necrosis.
Co-author:
WG Bian, DC Li, Q Lian, ect
Translation or Not:
No
Date of Publication:
2011-09-02

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